African Journal of Respiratory Medicine

Cycle threshold as a measure of infectivity from Covid-19 PCR tests

Abstract
Author(s): Alberto Boretti*

The Covid-19 polymerase-chain-reaction (PCR) test run with a cycle threshold of 40 returns as positive also cases of patients only having a small number of viral fragments in the sample. This produces an overrated number of those who are considered infected. It is suggested to always include the cycle number for positivity in the test result, as well as to lower the cycle threshold to 30-35 for more appropriate detection of those contagious

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